Coevolution at the proteome scale - Institute for Protein Design
Coevolution at the proteome scale - Institute for Protein Design
Today we report in Science the identification of hundreds of previously uncharacterized protein–protein interactions in E. coli and the pathogenic bacterium M. tuberculosis. These include both previously unknown protein complexes and previously uncharacterized components of known complexes. This research was led by postdoctoral fellow Qian Cong and included former Baker lab graduate student Sergey Ovchinnikov, now a John Harvard Distinguished Science
PDF) Large-scale discovery of protein interactions at residue resolution using co-evolution calculated from genomic sequences
Improved protein structure prediction using predicted interresidue orientations
IJMS, Free Full-Text
Exploiting enzyme evolution for computational protein design: Trends in Biochemical Sciences
Structural prediction of protein interactions and docking using conservation and coevolution - Andreani - 2020 - WIREs Computational Molecular Science - Wiley Online Library
Protein structure prediction - Wikipedia
Deploying synthetic coevolution and machine learning to engineer protein- protein interactions
Physics-Based Computational Protein Design: An Update
Protein interaction networks revealed by proteome coevolution
